INHIBITORY EFFECT OF PYRAZOLE DERIVATIVES ON THE P-NITROPHENYL PHOSPHATE PHOSPHATASE ACTIVITY OF ALKALINE PHOSPHATASE

UDC 542.978+577.15.025

Authors

  • L. Penkova, Engineer Taras Shevchenko National University of Kyiv image/svg+xml
  • V. Pavlenko, Cand. Sci. (Chem.) Taras Shevchenko National University of Kyiv image/svg+xml
  • O. Prysiazhna, Cand. Sci. (Chem.) Taras Shevchenko National University of Kyiv image/svg+xml
  • I. Fritsky, DSc (Chemistry) Taras Shevchenko National University of Kyiv image/svg+xml

Keywords:

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Abstract

Inhibition efficiency of the catalytic activity of alkaline phosphatase by novel 3,5-substituents of 1H-pyrazolate was examined. This indicates that among four tested compounds there are competitively and uncompetitively inhibitors. It was shown that magnesium ions do not influence on inhibitor effect.

References

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Published

2007-05-18

Issue

Vol. 46 No. 1 (2008): Bulletin Taras Shevchenko National University of Kyiv. Chemistry

Section

Articles

License

Copyright (c) 2007 Л. Пенкова, інж., В. Павленко, канд. хім. наук, О. Присяжна, канд. хім. наук, І. Фрицький, д-р хім. наук

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How to Cite

INHIBITORY EFFECT OF PYRAZOLE DERIVATIVES ON THE P-NITROPHENYL PHOSPHATE PHOSPHATASE ACTIVITY OF ALKALINE PHOSPHATASE: UDC 542.978+577.15.025. (2007). Bulletin of the Taras Shevchenko National University of Kyiv. Chemistry, 46(1), 19-21. https://chemistry.bulletin.knu.ua/article/view/8371

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