INFLUENCE OF SURFACTANTS ON THE FLUORESCEIN FLUORESCENCE PROPERTIES
DOI: https://doi.org/10.17721/1728-2209.2018.1(55).10
Keywords:
fluorescence, surface-active substances, fluorescein, cetylpyridinium chloride, sodium dodecyl sulfate, ethoniumAbstract
The use of fluorescence as an analytical signal makes it possible to reduce the limits of detection of analytes. The study of spectral properties of luminophores is important for the development of new methods for analyzing various objects. The use of micellar systems enables to increase quantum yields by 2–10 times and fluorescence intensity by 3–80 times and reduce the limits of detecting analytes by 1–2 orders of magnitude. Organized media based on surfactants influence on the fluorescence of luminescent indicators and their complex compounds due to changes in their microspheric solution of their photophysical characteristics, aggregate state and microprobe nature. Cationic surfactants occupy a special place among cytotoxicants. Low levels of maximum permissible concentrations of cationic surfactants require the use of sensitive analytical methods that combine simplicity and availability with reliability and expressiveness. Known chemical and microbiological methods for the determination of cationic surface-active antiseptics, disinfectants and preservatives characterize by complexity and labor intensity and are not suitable for the operational control of their concentration in places of local use. Therefore, the purpose of the work was to study the influence of various types of surfactants on the fluorescence properties of fluorescein to develop a method for determining the content of ethonium. The influence of surface-active substances of different types on the fluorescence properties of fluorescein was investigate. The anionic surfactant almost does not effect on the intensity of the dye signal. Nonionic surfactant leads to a gradual decrease in the fluorescence intensity of fluorescein. The most visible influence was observe with adding into the solution cationic surface-active substances. There is harsh intensity decrease of the dye fluorescence with subsequent exit to the "plateau" in the system of fluorescein-cetylpyridinium chloride. The cationic surfactant ethonium works the same. Received results will laid in the basis of the method development of ethonium determination in the medical drugs.
References
1. Желобицкая Е.А., Паращенко И.И., Смирнова Т.Д. // Изв. Сарат. ун-та. Нов. сер. Химия. Биология. Экология, 2012. –Т. 14. – С. 10–13.
Zhelobickaja E.A., Parashhenko I.I., Smirnova T.D. Izv. Sarat. un-ta. Nov. ser. Himija. Biologija. Jekologija, 2012, 14, 10–13. (In Russian).
2. Piñeiro L., Novo M., Al-Soufi W., Adv. Colloid Interface Sci., 2015, 215, 1–12.
3. Ge W., Shi H., Talmon Y., Hart D. J., Zakin J. L., J. Phys. Chem., 2011, 115, 5939–5946.
4. Liu G.-Y., Liu X.-S., Wang S.-S., Chen C.-J., Ji J., Langmuir, 2012, 28, 557–562.
5. Саввин С.Б. Поверхностно-активные вещества / С.Б. Саввин,
Р.К. Чернова, С.Н. Штыков. – М. : Наука, 1991. – С. 173–183.
Savvin S.B., Chernova R.K., Shtykov S.N. Surface-active substances. Moscow: Nauka, 1991, 173–183. (in Russian).
6. Mikhaleva N.M., Kulapina E.G., Mikhaleva O.V., Pharm. Chem. J., 2008, 42, 224–227.
7. Нашин С. М. Справочник по антибиотикам / С.М. Нашин, И.П. Фо-мина. М. : Медицина, 1984. – 46 c.
Nashin S. M., Fomina I. P. Handbook of Antibiotic. Moscow: Medicina, 1984, 46 p. (in Russian).
8. Kulapina E. G., Chernova R. K., Makarova N. M., Pogorelova E. S., J. Analyt. Chem., 2014, 69, 211–236.
9. Андреев С.В., Беляев Е.С., Иванова А.О., Новикова Э.А., Ищенко А.А. // Изв. вузов. Химия и хим. технология, 2018. – Т. 61. – С. 4–9.
Andreev S.V., Beljaev E.S., Ivanova A.O., Novikova E.A., Ishhenko A.A. Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol, 2018, 61, 4–9. (In Russian).
10. Dogan A., Bascı N.E., Curr. Pharm. Anal., 2011, 7, 167–175.
11. Gonçalves A.R., do Nascimento L.D., Duarte G.H.B., Simas R.S., Jesus Soares A., Eberlin M.N., Marques L.A., Chromatographia, 2016, 79, 841–849.
12. Işık B.D., Acar E.T., Chromatographia, 2018, 81, 699–706.
13. Дяченко С.А., Матвеева И.Н., Попова В.М., Кузнецова С.В. // Ве-стн. Курск. гос. сельскохоз. академии, 2015. – Т. 7. – С. 178–179.
Djachenko S.A., Matveeva I.N., Popova V.M., Kuznecova S.V. Vestnik Kurskoj gosudarstvennoj sel'skohozjajstvennoj akademii, 2015, 7, 178–179. (In Russian).
14. Денисенко В.Н., Сало Д.Н. // Фармация, 1974. – Т. 5. – С. 83–84.
Denisenko V.N., Salo D.N. Farmacija, 1974, 5, 83–84. (In Russian).
15. Goo H. R., Choi J. S., Na D. H., Arch. Pharm. Res., 2009, 32, 201–206.
16. Lin L.-Z., Harnly J.M. J., Agric. Food Chem., 2007, 55, 1084–1096.
17. Абдуллабекова В.Н. // Вестн. фармации, 2009. – Т. 45. – С. 1–5.
Abdullabekova V.N. Vestnik farmacii, 2009, 45, 1–5. (In Russian).
18. Ломбоева С.С. Химия растительного сырья / С.С. Ломбоева‚ Л.М. Танхаева, Д.Н. Оленников, 2008. – С. 65–68.
Lomboeva S.S. ‚ Tanhaeva L.M., Olennikov D.N. Himija rastitel'nogo syr'ja, 2008, 65–68. (In Russian).
19. Кузьмина С.С.‚ Афанасьева А.С. : мат-лы ІІІ Всерос. конф. "Новые достижения в химии и химической технологии растительного сырья". – Барнаул, 2007. – С. 230–233.
Kuz'mina S.S.‚ Afanas'eva A.S. Materials of the 3rd All-Russian Conference "New achievements in chemistry and chemical technology of plant materials", Barnaul, 2007, 230–233. (in Russian).
20. Mchedlov-Petrosjan N.O., Salinas Mayorga R.J., Chem. Soc., Faraday Trans., 1992, 88, 3025–3032.
21. Mchedlov-Petrossyan N.O., Kukhtic V.I., Bezugliy V.D., J. Phys. Org. Chem., 2003, 16, 380–397.
22. Vodolazkaya N. A., Mchedlov-Petrossyan N. O., Bryleva E. Y., Functional Materials, 2010, 17, 470–476.
23. Chai M., Holley A.K., Kruskamp M., Chem. Commun., 2007, 2, 168–170.
24. Bryleva E.Y., Vodolazkaya, N.A., Mchedlov-Petrossyan N.O., J. Colloid Interface Sci., 2007, 316, 712–722.
25. Водолазкая Н.А. Кислотно-основные равновесия индикаторных красителей в организованных растворах / Н.А. Водолазкая, Н.О. Мчедлов-Петросян. – Х. : ХНУ им. В.Н. Каразина, 2014. – С. 102–130.
Vodolazkaja N.A., Mchedlov-Petrosjan N.O. Acid-base equilibria of indicator dyes in organized solutions. Kharkiv: V.N. Karazin Kharkiv National University, 2014, 102–130. (in Russian).
Downloads
Published
Issue
Section
License
Copyright (c) 2019 В. Кловак, С. Лелюшок, С. Куліченко, О. Запорожець
This work is licensed under a Creative Commons Attribution 4.0 International License.
